Durham, NC, United States of America

Marcos Sznaidman



Average Co-Inventor Count = 3.4

ph-index = 4

Forward Citations = 106(Granted Patents)


Company Filing History:


Years Active: 2001-2013

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12 patents (USPTO):Explore Patents

Title: **Innovator Spotlight: Marcos Sznaidman**

Introduction

Marcos Sznaidman, an accomplished inventor based in Durham, NC, has made significant contributions to the field of nucleoside chemistry. With a robust portfolio of 12 patents, Sznaidman is recognized for his innovative approaches in developing processes that aid in the synthesis of enantiomerically pure compounds.

Latest Patents

Among his most recent innovations is a patented method to manufacture 1,3-dioxolane nucleosides. This application outlines a comprehensive process for preparing enantiomerically pure β-D-dioxolane nucleosides, emphasizing a novel synthesis of (−)-DAPD, which is particularly suited for large-scale development. The patented process includes several steps: obtaining esterified 2,2-dialkoxy ethanol, cyclizing it with glycolic acid to formulate a 1,3-dioxolane lactone, resolving the lactone to achieve purity, and reducing it to obtain a pure D- or L-1,3-dioxolane. Furthermore, Sznaidman’s invention details the coupling of the resulting compound with activated purine or pyrimidine bases, along with options for the purification of the nucleoside.

Career Highlights

Throughout his career, Sznaidman has worked with reputed organizations, including SmithKline Beecham Corporation and Emory University, where he honed his skills and expanded his knowledge in the field. His commitment to advancing nucleoside chemistry has positioned him as a prominent figure among his peers.

Collaborations

Sznaidman has collaborated with esteemed colleagues in his field, including George R. Painter and Merrick R. Almond. These partnerships reflect a strong network of professionals dedicated to innovation and excellence in research.

Conclusion

In conclusion, Marcos Sznaidman stands out as a noteworthy inventor whose work in nucleoside synthesis is paving the way for advancements in pharmaceutical development. With his impressive number of patents and collaborative efforts, he continues to impact the scientific community positively.

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