The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 2005
Filed:
Mar. 29, 2002
Applicant:
Marcos Sznaidman, Durham, NC (US);
Inventor:
Marcos Sznaidman, Durham, NC (US);
Assignee:
Triangle Pharmaceuticals, Durham, NC (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H019/19 ; C07H019/06 ;
U.S. Cl.
CPC ...
Abstract
The present invention is directed to the process for the preparation of 2'-deoxy-2′-halo-β-L-arabinofuranosyl nucleosides, and in particular, 2′-deoxy-2′-fluoro-β-L-arabinofuranosyl thymine (L-FMAU), from L-arabinose, which is commercially available and less expensive than L-ribose or L-xylose, in ten steps. All of the reagents and starting materials are inexpensive and no special equipment is required to carry out the reactions.