Location History:
- Roslindale, MA (US) (2010)
- Boston, MA (US) (2009 - 2014)
Company Filing History:
Years Active: 2009-2014
Title: Discovering Innovations: The Journey of Inventor Marc Jacobs
Introduction
Marc Jacobs, an accomplished inventor based in Boston, MA, has made significant contributions to the field of biotechnology, holding a total of five patents. His work is particularly notable in the area of human Janus Kinase 3 (JAK3), which plays a crucial role in various biological processes.
Latest Patents
Among his latest inventions is a patent for the "Crystal structure of human JAK3 kinase domain complex and binding pockets thereof." This groundbreaking invention focuses on the structural characteristics of JAK3 and its homologous binding pockets. The patent details a computer system with a data storage medium that encodes the structure coordinates of these binding pockets. The invention also outlines methodologies for solving the structures of homologous proteins or protein complexes. Furthermore, it provides innovative methods to screen for and design compounds, including inhibitory compounds that interact with the JAK3 protein or its homologues. The patent additionally includes crystallizable compositions and crystals that consist of the JAK3 kinase domain and JAK3 kinase domain complexed with AMP-PNP.
Career Highlights
Currently, Marc Jacobs works at Vertex Pharmaceuticals, Inc., a leader in biotechnology known for its innovative pursuit of therapies for debilitating diseases. Throughout his career, Jacobs has focused on advancing molecular biology through his extensive research and patent work.
Collaborations
In his journey, Jacobs has collaborated with accomplished coworkers, including Lovorka Swenson and Harmon J Zuccola. These collaborations have undoubtedly enriched his research endeavors and contributed to the success of his innovative projects.
Conclusion
Marc Jacobs stands out as a pioneering inventor whose work on JAK3 and its binding pockets showcases the potential for innovative therapies in the field of biotechnology. With his impressive portfolio of patents and collaborative efforts, Jacobs continues to inspire future innovations that aim to improve human health and understanding of complex biological systems.