Location History:
- Pune, IN (2013)
- Maharashta, IN (2020)
Company Filing History:
Years Active: 2013-2020
Title: Innovations by Manish Maheshkumar Gautam
Introduction
Manish Maheshkumar Gautam is a notable inventor based in Maharashtra, India. He has made significant contributions to the field of vaccine formulation, holding 2 patents that showcase his innovative approaches. His work focuses on improving the stability and efficacy of vaccine formulations, particularly in the context of pneumococcal vaccines.
Latest Patents
One of his latest patents is titled "Methods for improving the adsorption of polysaccharide-protein conjugates and multivalent vaccine formulation obtained thereof." This invention provides methods for the preparation of stable multivalent pneumococcal polysaccharide-protein conjugate vaccine formulations. The present invention outlines optimal conditions for percent adsorption of each conjugate, preventing aggregation through various techniques. These include individual adsorption for conjugates with lower percent adsorption, the use of a histidine-succinic acid buffer system with a pH shift, maintaining a polysaccharide to protein ratio between 0.5 to about 1.4, and employing a six-bladed Rushton type turbine impeller in formulation vessels.
Another significant patent is "Adjuvant composition for vaccine," which provides a fraction rich in withanolides to be used as an adjuvant in vaccine formulations. This innovative approach enhances the effectiveness of vaccines, contributing to better health outcomes.
Career Highlights
Manish Maheshkumar Gautam is currently associated with the Serum Institute of India Private Limited, a leading organization in vaccine production. His role at the institute allows him to apply his innovative ideas in a practical setting, contributing to the development of life-saving vaccines.
Collaborations
Throughout his career, Manish has collaborated with esteemed colleagues such as Suresh Sakharam Jadhav and Bhushan Patwardhan. These collaborations have further enriched his research and development efforts in the field of vaccine technology.
Conclusion
Manish Maheshkumar Gautam's contributions to vaccine formulation through his patents demonstrate his commitment to advancing public health. His innovative methods and collaborative efforts position him as a key figure in the field of immunology.