The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2020
Filed:
Jun. 03, 2016
Serum Institute of India Private Ltd., Hadapsar, Pune, Maharashta, IN;
Rajeev Mhalasakant Dhere, Maharashta, IN;
Hitesh Kumar Malviya, Maharashta, IN;
Swapan Kumar Jana, Maharashta, IN;
Sambhaji Shankar Pisal, Maharashta, IN;
Asha Dinesh Mallya, Maharashta, IN;
Sunil Mahor, Maharashta, IN;
Manish Maheshkumar Gautam, Maharashta, IN;
Chetan Vilas Joshi, Maharashta, IN;
Venkata Vamsi Krishna Malepati, Maharashta, IN;
Prashant Shivaji Jadhav, Maharashta, IN;
Serum Institute of India Private Ltd., Hadapsar, IN;
Abstract
The present invention provides methods for preparation of stable multivalent pneumococcal polysaccharide-protein conjugate vaccine formulations. Instant stable formulations show optimal percent adsorption for each conjugate wherein, aggregation can be prevented by employing i) Individual or separate adsorption for conjugates that otherwise show lower percent adsorption by combined adsorption ii) Histidine-Succinic acid buffer system along with shift in pH from neutral pH to acidic pH iii) a polysaccharide to protein ratio between 0.5 to about 1.4 iv) a six-bladed Rushton type turbine impeller in formulation vessels.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile