Maninder S Hoba

Title: The Innovations of Maninder S Hoba

Introduction

Maninder S Hoba is a notable inventor based in Danville, CA (US). He has made significant contributions to the field of protein solubility and formulation. With a total of 2 patents, his work focuses on enhancing the solubilization, purification, and refolding of proteins, particularly those that are incorrectly folded or aggregated.

Latest Patents

Hoba's latest patents include a method for the formulation, solubilization, purification, and refolding of tissue factor pathway inhibitor (TFPI). This innovative method employs polyionic polymers to facilitate the solubilization and formulation of proteins. The compositions developed allow for the preparation of pharmaceutically acceptable TFPI at concentrations exceeding 0.2 mg/mL and even above 10 mg/mL. Another patent details a similar method of modifying protein solubility, emphasizing the importance of these compositions in the pharmaceutical industry.

Career Highlights

Throughout his career, Hoba has worked with various organizations, including Chiron Corporation. His expertise in protein chemistry has positioned him as a valuable asset in the field of biopharmaceuticals. His innovative approaches have contributed to advancements in the formulation of therapeutic proteins.

Collaborations

Hoba has collaborated with notable professionals in his field, including Glenn J Dorin and Bo H Arve. These collaborations have further enriched his research and development efforts, leading to impactful innovations.

Conclusion

Maninder S Hoba's contributions to protein solubility and formulation are noteworthy. His patents reflect a commitment to advancing biopharmaceutical technologies. His work continues to influence the development of effective therapeutic proteins.