Mani Bushan Kotala

This inventor holds 9 USPTO granted patents and 1 published patent application, plus 1 CIPO patent and 5 EPO patents. Top assignees: Nucana Plc, Laurus Labs Private Limited. Active years: 2017-2024.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Mani Bushan Kotala. Retrieved from https://idiyas.com/inventor/mani-bushan-kotala

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 9 (Patent Applications = 1)

% Patents Active = 77.8

CIPO Patents = 1 (Patent Applications = 3)

EPO Patents = 5 (Patent Applications = 9)

Average Co-Inventor Count = 2.8

ph-index = 2

Forward Citations = 43(Granted Patents)

Location History:

Telangana, IN (2020)
Mandal, IN (2022 - 2023)
Hyderabad, IN (2017 - 2024)

Company Filing History:

Laurus Labs Private Limited

patents

Years Active: 2017-2024

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9 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12054511 - Synthesis of phosphate derivatives (2024-08-06),

2. 11897913 - Synthesis of 3′-deoxyadenosine-5′-O-[phenyl(benzyloxy-L-alaninyl)]phosphate (NUC-738) (2024-02-13),

3. 11603382 - Diastereoselective synthesis of phosphate derivatives (2023-03-14),

4. 11414452 - Synthesis of phosphate derivatives (2022-08-16),

5. 11414451 - Floxuridine synthesis (2022-08-16),

6. 10774104 - Diastereoselective synthesis of phosphate derivatives (2020-09-15),

7. 10301321 - Process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof (2019-05-28),

8. 9856271 - Process for the preparation of dolutegravir and pharmaceutically acceptable salts thereof (2018-01-02),

9. 9834577 - Process for the preparation of gemcitabine-[phenyl(benzoxy-L-alaninyl)] phosphate (2017-12-05),

Title: The Innovative Contributions of Mani Bushan Kotala

Introduction

Mani Bushan Kotala is a prominent inventor based in Hyderabad, Telangana, India. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel compounds for cancer treatment. With a total of nine patents to his name, Kotala's work is recognized for its potential impact on medical science.

Latest Patents

Among his latest patents is the invention related to the synthesis of phosphate derivatives. This process involves the preparation of specific 5'-phosphoramidate nucleotide diastereoisomers, which include compounds useful in cancer treatment, such as NUC-3373. This compound is a 5-fluoro-2′-deoxyuridine-5′-O-[1-naphthyl(benzyloxy-L-alaninyl)] phosphate. Another notable patent is the synthesis of 3′-deoxyadenosine-5′-O-[phenyl(benzyloxy-L-alaninyl)] phosphate, known as NUC-738. This invention focuses on a novel process for preparing 3′-deoxyadenosine derivatives, particularly NUC-7738, which serves as an anticancer ProTide of deoxyadenosine.

Career Highlights

Throughout his career, Kotala has worked with several reputable companies, including Nucana Plc and Laurus Labs Private Limited. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in the pharmaceutical industry.

Collaborations

Some of his notable coworkers include Venkata Lakshmi Narasimha Rao Dammalapati and Hugh Griffith. Their collaboration has further enhanced the innovative work being done in the field of cancer treatment.

Conclusion

Mani Bushan Kotala's contributions to the field of pharmaceuticals through his patents and collaborations highlight his dedication to advancing medical science. His innovative work continues to pave the way for new treatments in cancer therapy.

Profile summary based on public USPTO records.