Hyderabad Telangana, India

Mani Bushan Kotala

USPTO Granted Patents = 9 

 

 

Average Co-Inventor Count = 2.8

ph-index = 2

Forward Citations = 42(Granted Patents)


Location History:

  • Telangana, IN (2020)
  • Mandal, IN (2022 - 2023)
  • Hyderabad, IN (2017 - 2024)

Company Filing History:


Years Active: 2017-2024

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9 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Mani Bushan Kotala

Introduction

Mani Bushan Kotala is a prominent inventor based in Hyderabad, Telangana, India. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel compounds for cancer treatment. With a total of nine patents to his name, Kotala's work is recognized for its potential impact on medical science.

Latest Patents

Among his latest patents is the invention related to the synthesis of phosphate derivatives. This process involves the preparation of specific 5'-phosphoramidate nucleotide diastereoisomers, which include compounds useful in cancer treatment, such as NUC-3373. This compound is a 5-fluoro-2′-deoxyuridine-5′-O-[1-naphthyl(benzyloxy-L-alaninyl)] phosphate. Another notable patent is the synthesis of 3′-deoxyadenosine-5′-O-[phenyl(benzyloxy-L-alaninyl)] phosphate, known as NUC-738. This invention focuses on a novel process for preparing 3′-deoxyadenosine derivatives, particularly NUC-7738, which serves as an anticancer ProTide of deoxyadenosine.

Career Highlights

Throughout his career, Kotala has worked with several reputable companies, including Nucana Plc and Laurus Labs Private Limited. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in the pharmaceutical industry.

Collaborations

Some of his notable coworkers include Venkata Lakshmi Narasimha Rao Dammalapati and Hugh Griffith. Their collaboration has further enhanced the innovative work being done in the field of cancer treatment.

Conclusion

Mani Bushan Kotala's contributions to the field of pharmaceuticals through his patents and collaborations highlight his dedication to advancing medical science. His innovative work continues to pave the way for new treatments in cancer therapy.

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