The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 06, 2024
Filed:
Aug. 15, 2022
Applicant:
Nucana Plc, Central Scotland, GB;
Inventors:
Hugh Griffith, Central Scotland, GB;
Gordon Kennovin, Central Scotland, GB;
Venkata Lakshmi Narasimha Rao Dammalapati, Hyderabad, IN;
Mani Bushan Kotala, Hyderabad, IN;
Assignee:
NuCana plc, Edinburgh, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/207 (2006.01); C07H 1/02 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01);
U.S. Cl.
CPC ...
C07H 19/207 (2013.01); C07H 1/02 (2013.01); C07H 19/10 (2013.01); C07H 19/20 (2013.01);
Abstract
The present invention is a process for the preparation of certain 5'-phosphoramidate nucleotide diastereoisomers. The phosphoramidates include those useful in the treatment of cancer such as NUC-3373 (5-fluoro-2′-deoxyuridine-5′-O-[1-naphthyl(benzyloxy-L-alaninyl)]phosphate].