Company Filing History:
Years Active: 1997-2016
Title: The Innovative Contributions of Manfred Brockhaus
Introduction
Manfred Brockhaus, an esteemed inventor based in Bettingen, Switzerland, has made significant contributions to the field of biotechnology, particularly in the development of antibodies. With a total of nine patents to his name, his work has advanced the understanding and diagnostic capabilities surrounding amyloid-beta peptides, which are crucial in the study of neurodegenerative diseases such as Alzheimer's.
Latest Patents
One of Manfred Brockhaus's latest inventions focuses on "Antibodies against amyloid beta 4 with glycosylation in the variable region." This innovative patent pertains to a purified antibody molecule preparation characterized by at least one antigen binding site containing a glycosylated asparagine (Asn) in the variable region of the heavy chain (V). The invention includes pharmaceutical and diagnostic compositions that utilize these antibody molecules, capable of specifically recognizing the β-A4 peptide/Aβ4. Furthermore, it details the composition of antibody mixtures that incorporate glycosylated antigen binding sites, emphasizing the mixture of isoforms with glycosylated Asn in the heavy chain's variable region. The implications of this invention extend to pharmaceutical interventions targeting amyloidogenesis and the diagnosis of conditions associated with amyloid plaque formation.
Career Highlights
Throughout his career, Manfred has contributed to major advancements in the field while working with renowned companies, including Hoffmann-La Roche Inc. and F. Hoffmann-La Roche AG. His expertise has positioned him as a valuable innovator in the biotechnology sector, allowing him to leverage his skills in antibody development and therapeutic applications.
Collaborations
In his journey as an inventor, Manfred Brockhaus has collaborated with notable colleagues, including Bernd Bohrmann and Walter Huber. These partnerships have enriched his research and development endeavors, facilitating the creation of advanced antibody technologies that address critical health challenges.
Conclusion
Manfred Brockhaus exemplifies the spirit of innovation and dedication to advancing biotechnology through his prolific work as an inventor. With nine patents, particularly in the realm of antibody development, his contributions have far-reaching implications for diagnostics and therapeutics in neurodegenerative disorders. As he continues to forge new paths in research, the scientific community eagerly anticipates the future impact of his innovations.