The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 10, 2012
Filed:
Jul. 28, 2009
Michael Bardroff, München, DE;
Bernd Bohrmann, Freiburg, DE;
Manfred Brockhaus, Bettingen, CH;
Walter Huber, Kaiseraugst, CH;
Titus Kretzschmar, Hurlach, DE;
Hansruedi Loetscher, Möhlin, CH;
Corinna Löhning, Stockdorf, DE;
Christer Nordstedt, Sodertalje, SE;
Christine Rothe, Dachau, DE;
Michael Bardroff, München, DE;
Bernd Bohrmann, Freiburg, DE;
Manfred Brockhaus, Bettingen, CH;
Walter Huber, Kaiseraugst, CH;
Titus Kretzschmar, Hurlach, DE;
Hansruedi Loetscher, Möhlin, CH;
Corinna Löhning, Stockdorf, DE;
Christer Nordstedt, Sodertalje, SE;
Christine Rothe, Dachau, DE;
F. Hoffmann-La Roche AG, Basel, CH;
MorphoSys AG, Martinsried, DE;
Abstract
The present invention relates to antibody molecules capable of specifically recognizing two regions of the β-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a fragment thereof. Furthermore, nucleic acid molecules encoding the inventive antibody molecules and vectors and hosts comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions, preferably pharmaceutical or diagnostic compositions, comprising the compounds of the invention as well as for specific uses of the antibody molecules, nucleic acid molecules, vectors or hosts of the invention.