Location History:
- Juelich, DE (1992)
- J ulich, DE (1997 - 1999)
Company Filing History:
2 out of 304 
1 out of 204 
Years Active: 1992-1999
Title: Manfred Biselli: Innovator in Cell Cultivation Technologies
Introduction
Manfred Biselli is a notable inventor based in Munich, Germany. He has made significant contributions to the field of cell cultivation, holding a total of 3 patents. His innovative approaches have advanced the methods used in cultivating organ-function cells, which are crucial for various medical applications.
Latest Patents
One of Biselli's latest patents involves culturing cells on macroporous glass carriers coated with gelatin. This method allows for the cultivation of stem cells or other organ-function cells in a fluidized bed system. The process includes treating macroporous glass carrier bodies with structural proteins such as gelatin and extracellular matrix proteins like fibronectin. The glass carriers are added to a fluidized bed reactor, where a culture medium is introduced to bind the proteins to the gelatin. Stromal cells are then added, and the cells are cultured to immobilize them on the carriers. Immature organ-function cells are introduced into the reactor, and the culture medium is recirculated to maintain a fluidized bed. This innovative technique enables the cultivation of both mature differentiated organ-function cells and progenitor organ-function cells, ensuring a balance between harvested mature cells and those still adhering to the carriers.
Another patent focuses on a gasification-tube module and reactor for cell cultivation. This design features one or more gasification modules where tubular membrane hoses surround rigid inner tubes. These tubes communicate with gas inlets or outlets, enhancing the efficiency of the cell culture process.
Career Highlights
Throughout his career, Manfred Biselli has worked with esteemed organizations such as Forschungszentrum Jülich GmbH. His work has been instrumental in developing advanced technologies for cell cultivation, contributing to the scientific community's understanding of organ-function cell development.
Collaborations
Biselli has collaborated with notable colleagues, including Christian Wandrey and Bernd Schroder. These partnerships have fostered innovation and have been pivotal in advancing research in cell cultivation technologies.
Conclusion
Manfred Biselli's contributions to the field of cell cultivation are significant and impactful. His innovative patents and collaborations have paved the way for advancements in medical research and applications. His work continues to influence the development of technologies that are essential for cultivating organ-function cells.