Uppsala, Sweden

Makonnen Belew

USPTO Granted Patents = 9 


Average Co-Inventor Count = 2.7

ph-index = 6

Forward Citations = 126(Granted Patents)


Company Filing History:


Years Active: 1999-2011

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9 patents (USPTO):Explore Patents

Title: Makonnen Belew: Innovator in Anion-Exchange Technologies

Introduction

Makonnen Belew is a distinguished inventor based in Uppsala, Sweden. He has made significant contributions to the field of anion-exchange technologies, holding a total of nine patents. His innovative methods have advanced the purification processes in biochemistry and biotechnology.

Latest Patents

Among his latest patents is a method for anion-exchange adsorption and thioether anion-exchangers. This method focuses on the removal of negatively charged substances from aqueous liquids. It involves contacting the liquid with an anion-exchanger that contains mixed mode anion-exchanging ligands. These ligands feature a positively charged nitrogen that facilitates binding with the target substance. The method also includes desorbing the substance from the anion-exchanger, showcasing a breakthrough capacity that significantly exceeds conventional methods.

Another notable patent is a method for purifying recombinant human serum albumin (rHSA). This method utilizes a bimodal high salt tolerant matrix for cation exchange, hydrophobic interaction chromatography, and anion exchange. The innovative approach allows for direct purification from cell culture supernatants without the need for further dilution. This efficiency leads to substantial savings in both volume and operational costs.

Career Highlights

Makonnen Belew has worked with prominent companies in the biotechnology sector, including GE Healthcare Bio-Sciences AB and Amersham Biosciences AB. His experience in these organizations has contributed to his expertise in developing advanced purification techniques.

Collaborations

Throughout his career, Makonnen has collaborated with notable professionals in the field, including Bo-Lennart Johansson and Jean-Luc Maloisel. These partnerships have fostered innovation and the sharing of knowledge in biochemistry.

Conclusion

Makonnen Belew's contributions to anion-exchange technologies and purification methods have made a significant impact in the biotechnology industry. His innovative patents and collaborations highlight his role as a leading inventor in this field.

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