The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 2004
Filed:
Sep. 16, 2002
Bo-Lennart Johansson, Uppsala, SE;
Mikael Andersson, Uppsala, SE;
Jan Gustavsson, Uppsala, SE;
Makonnen Belew, Uppsala, SE;
Jean-Luc Maloisel, Enebyberg, SE;
Amersham Biosciences AB, Uppsala, SE;
Abstract
A method for the removal of a substance carrying a negative charge and being present in an aqueous liquid (I). The method comprises the steps of: (i) contacting the liquid with a matrix carrying a plurality of ligands comprising a positively charged structure and a hydrophobic structure, and (ii) desorbing the substance. The characterizing feature is that (I) each of said ligands together with a spacer has the formula: —SP—[Ar—R —N (R R R )] where (A) [Ar—R —N (R R R )] represents a ligand a) Ar is an aromatic ring, b) R is [(L) R′ ] where n and m are integers selected amongst zero or 1; L is amino nitrogen, ether oxygen or thioether sulphur; R′ is a linker selected among 1) hydrocarbon groups; 2) —C(═NH)—; c) R are selected among hydrogen and alkyls; (B) SP is a spacer providing a carbon or a heteroatom directly attached to Ar—R —N (R R R ); (C)—represents that SP replaces a hydrogen in (Ar—R —N (R R R ); (D)—represents binding to the matrix; and (II) desorption. There is also described (a) anion-exchangers having high breakthrough capacities, (b) a screening method and (c) a desalting protocol.