M Josefina Coloma

Title: M Josefina Coloma: Innovator in Immunology

Introduction

M Josefina Coloma is a notable inventor based in Santa Monica, California. She has made significant contributions to the field of immunology through her innovative research and development of modified immunoglobulin molecules. Her work focuses on enhancing the treatment and prevention of infectious diseases.

Latest Patents

M Josefina Coloma holds a patent for "Modified immunoglobulin molecules and methods for use thereof." This patent discloses modified immunoglobulin (Ig) molecules, methods for producing these modified Ig molecules, and their applications in treating and preventing infectious diseases. One embodiment of the modified Ig molecule includes a C,3 domain of an IgA molecule (α C,3). The combination of an α C,3 with other domains from non-IgA Ig molecules results in an Ig molecule capable of binding J chain and/or secretory component (SC), along with features of a non-IgA molecule. Another embodiment features a C,1 and/or C,2 domain of an IgA molecule, allowing for the formation of higher polymers while retaining characteristics of a non-IgA molecule. Additionally, the modified immunoglobulin molecule may lack one or more carbohydrate addition sites.

Career Highlights

M Josefina Coloma is affiliated with the University of California, where she continues her research and development efforts. Her work has garnered attention for its potential impact on public health and disease management.

Collaborations

M Josefina Coloma has collaborated with esteemed colleagues, including Sherie L Morrison and Koteswara R Chintalacharuvu. These collaborations have furthered her research and contributed to advancements in immunology.

Conclusion

M Josefina Coloma's innovative work in the field of immunology, particularly her patented modified immunoglobulin molecules, showcases her dedication to improving health outcomes. Her contributions are vital in the ongoing fight against infectious diseases.