Company Filing History:
Years Active: 2010-2021
Title: M Christina White: Innovator in Catalysis and Organic Chemistry
Introduction
M Christina White is a prominent inventor based in Champaign, IL (US). She has made significant contributions to the field of organic chemistry, particularly in the area of catalysis. With a total of 6 patents, her work has the potential to revolutionize small molecule therapeutics.
Latest Patents
One of her latest patents focuses on chemoselective methylene hydroxylation in aromatic molecules. This invention introduces a chemoselective and reactive Mn(CF-PDP) catalyst system. It enables the strategic advantages of late-stage aliphatic C—H hydroxylation to be leveraged in aromatic compounds. This discovery will benefit small molecule therapeutics by allowing for the rapid diversification of aromatic drugs and natural products, as well as the identification of their metabolites.
Another significant patent involves manganese (III) catalyzed C—H aminations. This invention addresses the challenge of directly installing nitrogen into C—H bonds of complex molecules. The reported manganese perchlorophthalocyanine catalyst [Mn(ClPc)] facilitates intermolecular benzylic C—H amination of bioactive molecules and natural products. It achieves unprecedented levels of reactivity and site-selectivity, demonstrating unique tolerance for various functionalities. Mechanistic studies indicate that C—H amination proceeds through an electrophilic metallonitrene intermediate, highlighting the innovative nature of her work.
Career Highlights
M Christina White is affiliated with the University of Illinois, where she continues to advance her research in catalysis and organic chemistry. Her innovative approaches have garnered attention in the scientific community, contributing to her reputation as a leading inventor in her field.
Collaborations
She has collaborated with notable colleagues, including Jinpeng Zhao and Mark S Chen, further enhancing the impact of her research through teamwork and shared expertise.
Conclusion
M Christina White's contributions to catalysis and organic chemistry are noteworthy, with her patents paving the way for advancements in small molecule therapeutics. Her innovative work continues to inspire and influence the scientific community.