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Title: Innovations of Luquan Wang in Protein Expression Optimization
Introduction
Luquan Wang is an accomplished inventor based in East Brunswick, NJ (US). He has made significant contributions to the field of biotechnology, particularly in the optimization of recombinant protein expression. With a total of 2 patents, his work has the potential to enhance the efficiency of protein production in various biological systems.
Latest Patents
One of Luquan Wang's latest patents is titled "Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm." This invention describes an improved gene sequence optimization method aimed at boosting the recombinant expression of genes in bacteria, yeast, insect, and mammalian cells. The method takes into account multiple parameters affecting protein expression, including codon usage, tRNA usage, GC-content, ribosome binding sequences, promoter, 5'-UTR, ORF, and 3'-UTR sequences. This systematic optimization can be incorporated into software for more efficient optimization.
Another notable patent is "NPC1L1 (NPC3) and methods of use thereof." This patent claims an isolated polypeptide that binds with cholesterol, which is useful for investigating the regulation of intestinal cholesterol absorption and cholesterol levels. The invention also includes a composition comprising the polypeptide bound to cholesterol or ezetimibe, as well as a fusion protein that includes the polypeptide.
Career Highlights
Luquan Wang has worked with several prominent companies in the biotechnology sector. Notable among these are Nanjing Jinsirui Science & Technology Biology Corporation and Schering Corporation. His experience in these organizations has contributed to his expertise in protein expression and optimization.
Collaborations
Luquan Wang has collaborated with several professionals in his field, including Xiaowu Liu and Yun He. These collaborations have likely enriched his research and contributed to his innovative approaches in biotechnology.
Conclusion
Luquan Wang's contributions to the field of protein expression optimization through his innovative patents demonstrate his significant impact on biotechnology. His work continues to pave the way for advancements in recombinant protein production.