Lung-Ji Chang

Title: Innovations of Lung-Ji Chang

Introduction

Lung-Ji Chang is a prominent inventor based in Gainesville, FL (US), known for his significant contributions to the field of immunotherapy. With a total of 11 patents to his name, he has made remarkable advancements in cancer treatment methodologies.

Latest Patents

Among his latest patents is a groundbreaking innovation in car-based immunotherapy. This patent discloses chimeric antigen receptors (CARs), T cells comprising such CARs, nucleic acids that encode these CARs, and methods for their use in treating cancers, particularly B cell malignancies. Another notable patent focuses on chimeric antigen receptors and their applications. This disclosure includes CARs with an antigen binding domain, transmembrane domain, and a cytoplasmic domain, along with a safety mechanism that features an inducible apoptosis trigger. These CARs are utilized in T cells, compositions, kits, and methods for treating thyroid cancers.

Career Highlights

Lung-Ji Chang has worked with the University of Florida Research Foundation, Incorporated, where he has furthered his research and development efforts. His work has been instrumental in advancing the understanding and treatment of various cancers through innovative approaches.

Collaborations

Throughout his career, Lung-Ji Chang has collaborated with notable colleagues, including Jan S Moreb and Jin He. These partnerships have contributed to the success of his research and the development of his patents.

Conclusion

Lung-Ji Chang's contributions to immunotherapy and cancer treatment through his patents highlight his role as a leading inventor in the field. His innovative approaches continue to pave the way for advancements in medical science.