Luca Domenighini

Title: Innovations of Luca Domenighini

Introduction

Luca Domenighini is a notable inventor based in Milan, Italy. He has made significant contributions to the field of pharmaceuticals, particularly in the purification of alkaloids and the development of new crystalline forms of medicinal compounds. With a total of two patents to his name, his work is recognized for its potential impact on cancer treatment.

Latest Patents

Luca's latest patents include a process for the purification of indole carbazole alkaloids. This process involves the salification of staurosporine by treatment with a mineral acid, leading to the isolation of a precipitated salt. Additionally, he has disclosed novel polymorphic forms of the mono- and bis-hydrochloride salts of staurosporine. Another significant patent is for a crystalline anhydrous form of Cabazitaxel, designated as form H. This invention includes a process for preparing form H through recrystallization from specific triglycerides. Form H is particularly useful as a medicament for cancer treatment.

Career Highlights

Luca Domenighini works at Indena S.p.A., a company known for its expertise in the development of plant-derived active ingredients for the pharmaceutical industry. His innovative approaches and research have contributed to the advancement of drug formulations and therapeutic applications.

Collaborations

Luca collaborates with esteemed colleagues, including Daniele Ciceri and Walter Cabri. Their combined expertise enhances the research and development efforts within their field.

Conclusion

Luca Domenighini's contributions to pharmaceutical innovations demonstrate his commitment to advancing medical science. His patents reflect a dedication to improving treatment options for cancer patients.