The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 07, 2017

Filed:

Oct. 09, 2014
Applicant:

Indena S.p.a., Milan, IT;

Inventors:

Walter Cabri, Milan, IT;

Daniele Ciceri, Milan, IT;

Luca Domenighini, Milan, IT;

Andrea Gambini, Milan, IT;

Federico Peterlongo, Milan, IT;

Assignee:

INDENA S.P.A., Milan, IT;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 305/14 (2006.01);
U.S. Cl.
CPC ...
C07D 305/14 (2013.01); C07B 2200/13 (2013.01);
Abstract

The present invention relates to a new anhydrous crystalline form of Cabazitaxel of formula (I), designated as form H. A further object of the present invention is a processes for the preparation of the above mentioned form H by recrystallization of Cabazitaxel from a mixture of decanoyl- and octanoyl triglycerides or from glycerol trioctanoate. Form H of Cabazitaxel is useful for the preparation of Cabazitaxel, Cabazitaxel salts, and polymorphic forms thereof. It is also particularly useful as a medicament, especially for the treatment of cancers.


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