Company Filing History:
Years Active: 2018
Title: Lotta Tolstoy Tegler: Innovator in Water-Soluble Membrane Proteins
Introduction
Lotta Tolstoy Tegler is a prominent inventor based in Linkoping, Sweden. She has made significant contributions to the field of biochemistry, particularly in the development of water-soluble membrane proteins. Her innovative work has implications for various applications in biotechnology and pharmaceuticals.
Latest Patents
Lotta holds a patent for "Water soluble membrane proteins and methods for the preparation and use thereof." This invention focuses on a method for preparing a water-soluble variant of a G-protein coupled receptor (GPCR). The method involves replacing specific hydrophobic residues in the transmembrane α-helical domain of the GPCR with hydrophilic amino acids, enhancing the protein's solubility.
Career Highlights
Lotta is affiliated with the Massachusetts Institute of Technology, where she continues her research and development in the field of membrane proteins. Her work has garnered attention for its potential to advance our understanding of GPCRs, which play a crucial role in cell signaling.
Collaborations
Lotta has collaborated with notable scientists such as Shuguang Zhang and Alexander Rich. These partnerships have enriched her research and contributed to the advancement of her innovative projects.
Conclusion
Lotta Tolstoy Tegler is a trailblazer in the field of water-soluble membrane proteins, with a patent that showcases her innovative approach to biochemistry. Her contributions are paving the way for future advancements in the understanding and application of GPCRs.