This inventor holds 3 USPTO granted patents. Top assignees: The United States of America, The United States of America as Represented by the Department of Health, The United States of America as Represented by the Secretary of. Active years: 1992-1997.
Company Filing History:



Years Active: 1992-1997
Title: Loris D McVittie: Innovator in Dopamine Receptor Research
Introduction
Loris D McVittie is a notable inventor based in Bethesda, MD (US). He has made significant contributions to the field of molecular biology, particularly in the study of dopamine receptors. With a total of 3 patents, his work has advanced our understanding of receptor mechanisms and their implications in health and disease.
Latest Patents
One of McVittie's latest patents is focused on cDNA encoding a rat D.sub.1 dopamine receptor linked to adenylyl cyclase. This invention relates to the molecular cloning and expression of the D.sub.1 dopamine receptor protein, which is crucial for assessing the affinities and efficacies of various drugs. The patent also includes a recombinant DNA construct that facilitates the expression of the D.sub.1 receptor in host cells, enabling further research and diagnostic applications. Another significant patent involves cDNA encoding the long isoform of the D.sub.2 dopamine receptor. This discovery highlights a novel G-protein coupled receptor isoform generated by alternative RNA splicing, which is predominantly expressed in the brain.
Career Highlights
Throughout his career, McVittie has worked with esteemed organizations, including the United States of America as represented by the Secretary of Health and the Department of Health. His research has been pivotal in understanding dopamine receptor functions and their roles in various physiological processes.
Collaborations
McVittie has collaborated with notable scientists such as David Robert Sibley and Frederick J Monsma, Jr. These partnerships have enriched his research and contributed to the advancement of knowledge in the field of neuroscience.
Conclusion
Loris D McVittie's innovative work in dopamine receptor research has led to significant advancements in molecular biology. His patents and collaborations continue to influence the scientific community and pave the way for future discoveries.