Durham, NC, United States of America

Lori Setton

This inventor holds 1 USPTO granted patent. Top assignees: Duke University, University of Utah Research Foundation. Active years: 2021.


% Patents Active = 100.0

Average Co-Inventor Count = 7.0

ph-index = 1


Company Filing History:


Years Active: 2021

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1 patent (USPTO):Explore Patents

Title: Lori Setton: Innovator in RNA-Guided Therapeutics

Introduction

Lori Setton is a prominent inventor based in Durham, NC (US). She has made significant contributions to the field of biomedical engineering, particularly in the area of RNA-guided transcriptional regulation. Her innovative work aims to address critical health issues, including back pain.

Latest Patents

Lori Setton holds a patent for "RNA-guided transcriptional regulation and methods of using the same for the treatment of back pain." This patent describes compositions and methods for the treatment and prevention of low back pain. The compositions include vectors comprising nucleotide sequences encoding one or more CRISPR-Cas system guide RNAs and an RNA-directed nuclease. The methods involve modulating gene expression in a cell using these compositions, introducing a CRISPR-Cas system into a cell, inducing site-specific DNA cleavage, and treating subjects with lower back pain, including pain caused by degenerative disc disease.

Career Highlights

Throughout her career, Lori Setton has worked with esteemed institutions such as Duke University and the University of Utah Research Foundation. Her research has focused on developing innovative solutions to complex medical problems, showcasing her dedication to improving patient outcomes.

Collaborations

Lori has collaborated with notable colleagues, including Jonathan M. Brunger and Robert Daniel Bowles. These partnerships have furthered her research and contributed to advancements in her field.

Conclusion

Lori Setton is a trailblazer in the realm of RNA-guided therapeutics, with a focus on treating back pain through innovative methods. Her contributions to science and medicine continue to pave the way for future advancements in healthcare.

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