Location History:
- Cranberry Twp., PA (US) (2013)
- Cranberry Township, PA (US) (2017)
Company Filing History:
Years Active: 2013-2017
Title: Lori Ann Emert-Sedlak: Innovator in HIV Treatment
Introduction
Lori Ann Emert-Sedlak is a prominent inventor based in Cranberry Township, PA (US). She has made significant contributions to the field of medical research, particularly in the development of compounds for treating HIV. With a total of 2 patents, her work focuses on innovative methods to combat this challenging virus.
Latest Patents
Emert-Sedlak's latest patents include groundbreaking research on compounds capable of treating HIV. One of her notable inventions involves a compound that inhibits Nef, acting as an antagonist of HIV Nef function. This compound can be used alone or in combination with other pharmacologically active agents to reduce drug resistance and cumulative toxicity. Another significant patent targets the HIV-1 nef-host cell kinase complex, identifying drug candidates that inhibit HIV-I replication by targeting Src family kinases (SFK) that interact with the Nef protein. Various inhibitors, such as 2,3-diaminoquinaxolines and furo[2,3-d]pyrimidines, have been found to effectively arrest HIV-I viral replication in vitro.
Career Highlights
Lori Ann Emert-Sedlak is affiliated with the University of Pittsburgh, where she continues her research and development efforts. Her work has garnered attention for its potential impact on HIV treatment and management.
Collaborations
Some of her notable coworkers include Billy W Day and Thomas E Smithgall, who have collaborated with her on various research projects.
Conclusion
Lori Ann Emert-Sedlak's innovative work in the field of HIV treatment showcases her dedication to advancing medical science. Her patents reflect a commitment to finding effective solutions for combating this virus, making her a valuable contributor to the field.