Location History:
- Monteriggioni, IT (2012)
- Siena, IT (2013 - 2020)
Company Filing History:
3 out of 531 
2 out of 3,923 
2 out of 50 
Years Active: 2012-2020
Title: Lorenzo Tarli: Innovator in Meningococcal Vaccine Development
Introduction
Lorenzo Tarli is a prominent inventor based in Siena, Italy, known for his significant contributions to the field of immunology. He holds a total of 8 patents, showcasing his innovative approach to vaccine development, particularly against serogroup B meningococcus.
Latest Patents
One of his latest patents focuses on the adjuvanting of meningococcal factor H binding protein (fHBP). This protein has been proposed for use in immunizing against serogroup B meningococcus ('MenB'). The patent details methods for efficiently adsorbing this antigen to an aluminum hydroxyphosphate adjuvant. Key aspects include ensuring that adsorption occurs at a pH equal to or below the adjuvant's point of zero charge (PZC), selecting a fHBP and adjuvant with an isoelectric point/PZC within the range of 5.0 to 7, and using a buffer to adjust the pH when necessary. This innovative approach is particularly beneficial for compositions that include multiple fHBP variants and in cases where aluminum hydroxide adjuvants should be avoided.
Career Highlights
Throughout his career, Lorenzo Tarli has worked with notable companies in the pharmaceutical industry, including GlaxoSmithKline Biologicals and Novartis AG. His work has significantly advanced the understanding and development of vaccines, particularly in the context of meningococcal diseases.
Collaborations
Lorenzo has collaborated with esteemed colleagues such as Mario Contorni and Dario Neri, contributing to the advancement of vaccine research and development.
Conclusion
Lorenzo Tarli's innovative work in the field of immunology, particularly regarding meningococcal vaccines, has made a lasting impact on public health. His patents and collaborations reflect a commitment to advancing medical science and improving vaccine efficacy.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.