The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2014
Filed:
Jul. 14, 2010
Luciano Zardi, Genoa, IT;
Dario Neri, Zuricu, CH;
Barbara Carnemolla, Genoa, IT;
Fredrik Nilsson, Stockholm, SE;
Lorenzo Tarli, Siena, IT;
Laura Borsi, Genoa, IT;
Cornelia Halin, Zurich, CH;
Luciano Zardi, Genoa, IT;
Dario Neri, Zuricu, CH;
Barbara Carnemolla, Genoa, IT;
Fredrik Nilsson, Stockholm, SE;
Lorenzo Tarli, Siena, IT;
Laura Borsi, Genoa, IT;
Cornelia Halin, Zurich, CH;
Philogen S.p.A., Siena, IT;
Abstract
Treatment of lesions of pathological angiogenesis, especially tumors, rheumatoid arthritis, diabetic retinopathy, age-related muscular degeneration, and angiomas. A conjugate is used comprising a molecule that exerts a biocidal or cytotoxic effect on target cells in the lesions and an antibody directed against an extracellular matrix component which is present in such lesions. The antibody may be directed against fibronectin-2 (IL-2), doxorubicin, interleukin-12 (IL-12), Interferon-γ (IFN-γ), Tumor Necrosis Factor α (TNFα) or Tissue Factor protein (which may be truncated).