Logan Tom

Title: Logan Tom: Innovator in DNA Sequencing Technologies

Introduction

Logan Tom is a prominent inventor based in Alameda, California. He has made significant contributions to the field of DNA sequencing, particularly through his innovative methods and compositions aimed at enhancing the accuracy of massive parallel sequencing.

Latest Patents

Logan Tom holds a patent for "Methods and compositions for reducing base errors of massive parallel sequencing using triseq sequencing." This patent encompasses two main parts. The first part involves ligating a UMI adapter, amplifying DNA fragments in the presence of dUTP, enriching target molecules through primer extension with both forward and reverse primers, and removing dU-containing template DNA. The DNA molecules are organized into primary clones and subclones, labeled by the UMI on the 5' and 3' ends of the DNA fragments, respectively. The second part of the patent details the sequencing of the DNA library by next-generation sequencing (NGS), deducing consensus sequences from each subclone, and between the consensus sequences obtained from both forward and reverse primers.

Career Highlights

Logan Tom is currently employed at Paragon Genomics, Inc., where he continues to advance the field of genomics through his research and innovations. His work has been instrumental in improving the efficiency and accuracy of DNA sequencing technologies.

Collaborations

Logan collaborates with notable colleagues, including Zhitong Liu and David Debruyne, who contribute to the innovative projects at Paragon Genomics, Inc.

Conclusion

Logan Tom's contributions to DNA sequencing technologies exemplify the impact of innovative thinking in the field of genomics. His patent and ongoing work at Paragon Genomics, Inc. highlight his commitment to advancing scientific research and improving sequencing methodologies.