This inventor holds 5 USPTO granted patents and 5 EPO patents. Top assignees: Lek Pharmaceuticals D.d., Other. Active years: 2007-2014.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2007-2014
Title: Ljubomir Antoncic: Innovator in Pharmaceutical Processes
Introduction
Ljubomir Antoncic is a notable inventor based in Ljubljana, Slovenia. He has made significant contributions to the field of pharmaceuticals, particularly in the preparation of atorvastatin calcium. With a total of 5 patents to his name, Antoncic's work has advanced the methods used in drug formulation.
Latest Patents
Among his latest patents is a process for the preparation of amorphous calcium salt of atorvastatin. This innovative process involves creating a reaction mixture with a pH between 6.5 and 8.0, which contains a sodium salt of atorvastatin and tetrahydrofuran. The method includes the addition of a non-cyclic chlorinated organic solvent, such as dichloromethane or chloroform, or a cyclic hydrocarbon solvent like cyclohexane. An equivalent or excess quantity of a source of calcium ions, such as calcium acetate or calcium chloride, is then added. The result is the isolation of amorphous atorvastatin calcium from the organic phase.
Another patent focuses on the preparation of amorphous atorvastatin calcium without the intermediate isolation of crystals. This process utilizes a mixture of chlorinated organic solvents or cyclic hydrocarbon solvents, along with water, to form calcium atorvastatin salt.
Career Highlights
Ljubomir Antoncic has worked with Lek Pharmaceuticals D.d., a prominent company in the pharmaceutical industry. His expertise in drug formulation has been instrumental in developing innovative processes that enhance the efficacy of medications.
Collaborations
Throughout his career, Antoncic has collaborated with notable colleagues, including Anton Copar and Gorazd Sorsak. These partnerships have contributed to the advancement of pharmaceutical research and development.
Conclusion
Ljubomir Antoncic's contributions to the field of pharmaceuticals through his innovative processes have made a significant impact. His work continues to influence the preparation of atorvastatin calcium and other pharmaceutical compounds.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile