The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 05, 2013
Filed:
Apr. 09, 2004
Applicants:
Ljubomir Antoncic, Ljubljana, SI;
Gorazd Sorsak, Ljubljana, SI;
Anton Copar, Smartno pri Litigi, SI;
Inventors:
Ljubomir Antoncic, Ljubljana, SI;
Gorazd Sorsak, Ljubljana, SI;
Anton Copar, Smartno pri Litigi, SI;
Assignee:
LEK Pharmaceuticals D.D., Ljubljana, SI;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/34 (2006.01);
U.S. Cl.
CPC ...
Abstract
Present invention refers to the process of preparing amorphous atorvastatin calcium without intermediate isolation of crystal or undefined mixture of crystal and amorphous atorvastatin calcium, respectively. Forming of calcium atorvastatin salt is carried out in a mixture of chlorinated organic solvent or cyclic hydrocarbon solvent, respectively, the non-hydroxylic organic solvent, and water, the source of calcium ions is calcium acetate or calcium chloride, respectively.