Company Filing History:
Years Active: 2013-2025
Title: Innovations by Inventor Lixin Wang from Tianjin, China
Introduction
Lixin Wang, an accomplished inventor based in Tianjin, China, has made significant contributions to the field of asymmetric synthesis and catalytic processes. With a total of six patents to his name, his research has paved the way for innovative solutions in the pharmaceutical industry.
Latest Patents
Lixin Wang's latest patents include notable advancements in kinetic resolution and ligand chemistry. One of his prominent inventions is focused on the "Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof." This invention details a method of achieving high optical purity chiral -hydroxyl esters and 1,5-diols through asymmetric catalytic hydrogenation. Utilizing a chiral spiro pyridyl phosphine ligand iridium catalyst, the process demonstrates remarkable enantioselectivity and yield while minimizing catalyst usage. The resulting chiral -hydroxyl esters and 1,5-diols hold critical significance in the synthesis of chiral drugs such as (R)-lisofylline and natural drugs like (+)-civet and (-)-coniine.
Additionally, another of Wang's patents is titled "Chiral spiro phosphorus-nitrogen-sulfur tridentate ligand, preparation method and application thereof." This invention presents a tridentate ligand characterized by a chiral spiro indan skeleton structure. The ligand can be utilized in asymmetric catalytic hydrogenation reactions, showcasing high catalytic activity and enantioselectivity, providing practical value for industrial applications.
Career Highlights
Lixin Wang's career has been marked by collaboration with prominent pharmaceutical companies such as Zhejiang Jiuzhou Pharmaceutical Co., Ltd., where he has applied his innovative research to real-world challenges. His work in the field of asymmetric synthesis is well-respected, contributing not only to academic knowledge but also to practical applications in pharmaceutical development.
Collaborations
Throughout his career, Lixin Wang has worked alongside talented individuals such as Qilin Zhou and Jianhua Xie. These collaborations have enhanced the research and development process, leading to impactful innovations in catalytic methods and synthesis.
Conclusion
Lixin Wang stands out as a key figure in the realm of inventive solutions for pharmaceutical applications. His groundbreaking patents contribute significantly to advancements in asymmetric synthesis, showcasing the importance of innovation in developing chiral drugs. As he continues his work, his contributions are poised to influence the pharmaceutical industry and inspire future inventors and researchers.
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