Company Filing History:
Years Active: 2012-2015
Title: Lishan Chen: Innovator in Gene Delivery Technologies
Introduction
Lishan Chen is a prominent inventor based in Bellevue, WA (US). He has made significant contributions to the field of gene delivery technologies, holding 2 patents that focus on enhancing the delivery of nucleic acids to regulate gene expression in mammalian cells.
Latest Patents
Chen's latest patents include innovative methods and compositions for enhancing the delivery of double-stranded RNA or hybrid nucleic acids. One of his notable inventions is a delivery-enhancing peptide that comprises the amino acid sequence of SEQ ID NO:11 or its salt. This invention aims to effectively administer double-stranded ribonucleic acid to mammals, facilitating transfection into targeted tissues. Another patent focuses on polynucleotide delivery-enhancing polypeptides that are complexed with nucleic acids to improve their delivery into cells. These compositions are designed to modulate gene expression through small inhibitory nucleic acids (siNAs), which can alter phenotypes in mammalian cells and potentially eliminate disease symptoms.
Career Highlights
Lishan Chen is currently associated with Marina Biotech, Inc., where he continues to advance his research in gene delivery systems. His work has positioned him as a key figure in the biotechnology sector, contributing to the development of effective tools for gene modulation.
Collaborations
Chen collaborates with notable colleagues, including Kunyuan Cui and Michael E Houston, Jr. These partnerships enhance the innovative potential of his research and contribute to the advancement of gene therapy technologies.
Conclusion
Lishan Chen's work in gene delivery technologies exemplifies the impact of innovative thinking in biotechnology. His patents provide valuable insights and tools for regulating gene expression, showcasing the importance of research in improving health outcomes.