Company Filing History:
3 out of 61 
1 out of 1,187 
Years Active: 2003-2012
Title: Innovations and Contributions of Linda A. Sherman
Introduction
Linda A. Sherman is a prominent inventor based in La Jolla, California. She has made significant contributions to the field of biotechnology, particularly in the development of binding molecules that have therapeutic applications. With a total of four patents to her name, her work has the potential to impact cancer treatment and immunotherapy.
Latest Patents
Among her latest patents is the invention of polyspecific binding molecules and their uses. This invention focuses on single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR) covalently linked through a peptide linker sequence to at least one single-chain antibody (sc-Ab). The patent also discloses methods and compositions for testing and utilizing these molecules. Another notable patent is for P53 binding T cell receptor molecules. This invention provides T-cell receptor (TCR) molecules that bind peptides derived from the p53 protein, specifically the human p53 protein. The TCR molecules include both heterodimeric and single-chain forms that specifically bind a sequence spanning amino acid positions 264-272 of the p53 protein displayed in the context of an HLA molecule, preferably HLA-A2.1. The invention has a wide spectrum of useful applications, including therapeutic uses and detection of cells expressing p53 protein.
Career Highlights
Linda has worked with several notable organizations, including Altor Bioscience Corporation and The Scripps Research Institute. Her experience in these institutions has allowed her to collaborate with leading experts in the field and contribute to groundbreaking research.
Collaborations
Some of her notable coworkers include Kimberlyn F. Card and Jon A. Weidanz. Their collaborative efforts have further advanced the research and development of innovative biotechnological solutions.
Conclusion
Linda A. Sherman is a distinguished inventor whose work in binding molecules has the potential to revolutionize therapeutic approaches in medicine. Her contributions to the field are invaluable and continue to inspire future innovations.