Lina Cui

Title: Innovations and Contributions of Inventor Lina Cui

Introduction

Lina Cui is a prominent inventor based in Mountain View, CA. She has made significant contributions to the field of medical imaging and drug delivery systems. With a total of 2 patents, her work focuses on enhancing the efficacy of treatments through innovative technologies.

Latest Patents

One of her latest patents is titled "Probe for imaging PARP-1 activity." This invention provides embodiments of a small molecule tracer for positron emission tomography (PET) imaging of the enzyme activity of PARP-1, which is crucial for DNA-damage sensing and plays a vital role in radiation therapy and chemotherapy response mechanisms. The PARP-1 tracers are derivatives of nicotinamide adenine dinucleotide (NAD), the natural substrate for PARP-1. These derivatives include a linker moiety that can be attached to a label moiety, such as a PET detectable fluorine, to generate a 6N-(triazo-PEG2-F)-NAD. The attachment of a chelating agent allows for the formation of a chelator-metal ion complex, making it especially advantageous for use in PET and MRI scanning detection systems.

Another notable patent is for "Amphiphilic cyclodextrin-based glycodendrimers." This application presents an amphiphilic cyclodextrin-based compound designed to enhance water solubility, bioavailability, and cellular uptake of active ingredients used in medicines, cosmetics, and foods. The compound can also be utilized for the detection, removal, and immobilization of pathogenic organisms, toxins, and biomarkers on solid matrices, as well as for molecular biological techniques such as ELISA.

Career Highlights

Lina Cui has worked with esteemed institutions, including Leland Stanford Junior University and Uti Limited Partnership. Her experience in these organizations has contributed to her innovative research and development efforts.

Collaborations

Throughout her career, Lina has collaborated with notable colleagues, including Adam Shuhendler and Jianghong Rao. These partnerships have fostered a collaborative environment that enhances the impact of her inventions.

Conclusion

Lina Cui's contributions to the fields of medical imaging and drug delivery systems exemplify her innovative spirit and dedication to advancing healthcare technologies. Her patents reflect a commitment to improving treatment efficacy and patient outcomes.