The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 24, 2018
Filed:
Oct. 01, 2014
Uti Limited Partnership, Calgary, CA;
Chang-Chun Ling, Calgary, CA;
Lina Cui, Mountan View, CA (US);
Ramprasad Ghosh, Halifax, CA;
Ping Zhang, Calgary, CA;
Aixia Wang, Calgary, CA;
UTI Limited Partnership, Calgary Alberta, CA;
Abstract
The present application provides an amphiphilic cyclodextrin-based compound of the formula I: R-G-D-A (I) wherein R is one or more hydrophilic groups; G is one or more linkers; D is a cyclodextrin, and A is one or more aliphatic groups. In certain embodiments, the hydrophilic group is a sugar such as lactose, the linker comprises —(CHR'CHO)— where R′ is H or is an alkyl group substituted with —(CHR′CHO)— where n is 1 to 20, typically n=4; the cyclodextrin is a β-cyclodextrin comprising 7 subunits, and the aliphatic groups are Calkyl groups. The compound can be used to enhance water solubility, bioavailability, cellular uptakes of active ingredients used in medicines, cosmetics and foods and other products, for detection, removal and immobilization of pathogenic organisms, toxins, and autoantibodies, and biomarkers on solid matrix, or for molecular biological techniques, such as ELISA, for example.