Company Filing History:
Years Active: 2012-2016
Title: Lin Jiang: Innovator in Computational Enzyme Design
Introduction
Lin Jiang is a prominent inventor based in Seattle, WA (US). He has made significant contributions to the field of enzyme design through innovative computational techniques. With a total of 2 patents, his work focuses on creating synthetic enzymes that can enhance various biochemical processes.
Latest Patents
One of Lin Jiang's latest patents involves the development of synthetic enzymes derived from computational design. This patent discloses techniques for computationally designing enzymes, which can be used to create variations of naturally occurring enzymes as well as entirely new enzymes that do not have natural counterparts. The process begins by identifying functional reactive sites necessary for promoting the desired reaction. Subsequently, hashing algorithms are employed to identify potential protein backbone structures, or scaffolds, that can support these functional sites. Using these techniques, Jiang successfully designed 32 different protein sequences that exhibit aldol reaction catalytic function, with 31 of these sequences detailed in the Sequence Listing. The patent also provides insights into how these synthetic aldolases can be differentiated from their naturally occurring counterparts.
Career Highlights
Lin Jiang is affiliated with the University of Washington, where he continues to push the boundaries of enzyme design. His innovative approach has garnered attention in the scientific community, contributing to advancements in biochemistry and synthetic biology.
Collaborations
Some of Lin Jiang's notable coworkers include David Baker and Alexandre Zanghellini. Their collaborative efforts have further enriched the research environment and fostered innovative solutions in enzyme design.
Conclusion
Lin Jiang's work in computational enzyme design exemplifies the intersection of technology and biology. His contributions are paving the way for new advancements in the field, showcasing the potential of synthetic enzymes in various applications.
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