Company Filing History:
1 out of 19 
1 out of 17 
1 out of 7 Years Active: 2018
Title: Lihui Liu: Innovator in Pharmaceutical Chemistry
Introduction
Lihui Liu is a prominent inventor based in Tianjin, China. She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on diketoreductase mutants.
Latest Patents
Lihui Liu holds a patent for a diketoreductase mutant and its applications. The patent details a Diketoreductase (DKR) mutant, its nucleotide coding sequence, and an expression cassette, recombinant vector, and host cell containing the sequence. The method described in the patent allows for the preparation of a 3R,5S-dicarbonyl compound, achieving an ee value higher than 99% and a de value of about 90%. This DKR mutant serves as a key pharmaceutical intermediate and provides an efficient catalyst for the synthesis of a chiral dicarbonyl hexanoic acid chain, which is essential for statin drug production.
Career Highlights
Throughout her career, Lihui Liu has worked with notable companies, including Asymchem Laboratories (Tianjin) Co., Ltd. and Asymchem Life Science (Tianjin) Co., Ltd. Her expertise in pharmaceutical chemistry has positioned her as a valuable asset in the industry.
Collaborations
Lihui Liu has collaborated with esteemed colleagues such as Hao Hong and James Gage. These partnerships have further enhanced her research and development efforts in the field.
Conclusion
Lihui Liu's innovative work in the development of diketoreductase mutants has made a significant impact on pharmaceutical chemistry. Her contributions continue to advance the synthesis of important pharmaceutical compounds.