Lihuang Chen

Title: Lihuang Chen: Innovator in Chemical Synthesis

Introduction

Lihuang Chen is a prominent inventor based in Shanghai, China. He has made significant contributions to the field of chemical synthesis, holding a total of 2 patents. His innovative approaches have led to advancements in the preparation of various chemical compounds.

Latest Patents

Lihuang Chen's latest patents include a synthesis method for 1-methyl-1H-indazole-6-carboxylic acid. This method utilizes 2-fluoro-4-bromobenzaldehyde and methylhydrazine as raw materials to produce 6-bromo-1-methylindazole through an annulation reaction. Following this, a methyl formate reaction and hydrolysis are performed to yield the desired compound. This synthesis method is notable for its ability to directly produce a 1-position methyl substituted indazole without isomers, thus enhancing product purity and achieving an impressive yield of 85% in the annulation reaction.

Another significant patent is the method for preparing 2-ethyl-4-fluoro-1-nitrobenzene. This process involves several steps, including the nitrification of 3-fluoroacetophenone, reduction of the resulting compound, iodination, and further reduction to obtain the final product. Each step is carefully designed to ensure efficiency and effectiveness in the synthesis process.

Career Highlights

Lihuang Chen is currently employed at Accela Chembio Co., Ltd., where he continues to innovate and develop new chemical synthesis methods. His work has been instrumental in advancing the capabilities of the company in the field of chemical research and development.

Collaborations

Throughout his career, Lihuang Chen has collaborated with notable colleagues, including Duoqing Xue and Yong Wu. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and enhances the quality of their research.

Conclusion

Lihuang Chen is a distinguished inventor whose contributions to chemical synthesis have made a significant impact in the field. His innovative methods and collaborative spirit continue to drive advancements in chemical research.