The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 21, 2023

Filed:

Sep. 10, 2020
Applicants:

Accela Chembio Co., Ltd., Shanghai, CN;

Qidong Accela Chembio Co., Ltd., Jiangsu, CN;

Inventors:

Yang Liu, Shanghai, CN;

Duoqing Xue, Shanghai, CN;

Yong Wu, Shanghai, CN;

Lihuang Chen, Shanghai, CN;

Lianhua Zhai, Shanghai, CN;

Assignee:

ACCELA CHEMBIO CO., LTD., Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 201/08 (2006.01); C07C 201/12 (2006.01);
U.S. Cl.
CPC ...
C07C 201/08 (2013.01); C07C 201/12 (2013.01);
Abstract

The present disclosure provides a method for preparing 2-ethyl-4-fluoro-1-nitrobenzene, including: (1) nitrifying 3-fluoroacetophenone with a nitration reagent, to obtain 1-(5-fluoro-2-nitrophenyl)ethanone; (2) reducing 1-(5-fluoro-2-nitrophenyl)ethanone with a reducing agent, to obtain 4-fluoro-2-(1-hydroxyethyl)-1-nitrobenzene; (3) iodinating 4-fluoro-2-(1-hydroxyethyl)-1-nitrobenzene, to obtain 4-fluoro-2-(1-iodoethyl)-1-nitrobenzene; and (4) reducing 4-fluoro-2-(1-iodoethyl)-1-nitrobenzene with a reducing agent, to obtain 2-ethyl-4-fluoro-1-nitrobenzene.


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