Liangfeng Jiang

Title: Innovations by Liangfeng Jiang in Antibody Development

Introduction

Liangfeng Jiang is a prominent inventor based in Shanghai, China, known for his significant contributions to the field of biotechnology. He has been instrumental in developing innovative antibodies that target specific human proteins, which have promising applications in treating various diseases.

Latest Patents

Liangfeng Jiang holds two notable patents. The first patent is for antibodies binding to human IL-4R, which are designed to treat diseases related to IL-4R overexpression, such as atopic dermatitis and asthma. These antibodies feature identical variable regions and different constant regions, allowing for specific binding to human IL-4R while enhancing the antibody's overall activity through amino acid site mutations. The second patent involves a monoclonal antibody that binds to human IL-5. This antibody effectively inhibits TF-1 cell proliferation induced by IL-5 and blocks the interaction between IL-5 and IL-5RA. It has a different antigen epitope compared to existing anti-human IL-5 antibodies and shows potential for treating diseases mediated by eosinophilic granulocyte overexpression, such as asthma.

Career Highlights

Liangfeng Jiang is currently employed at Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd., where he continues to advance his research in antibody development. His work has garnered attention for its clinical application prospects, particularly in the treatment of respiratory diseases.

Collaborations

Liangfeng collaborates with notable colleagues, including Jie Zhao and Haomin Huang, who contribute to his research efforts and innovations in the field.

Conclusion

Liangfeng Jiang's innovative work in antibody development positions him as a key figure in biotechnology, with the potential to significantly impact the treatment of various diseases. His patents reflect a commitment to advancing medical science and improving patient outcomes.