Company Filing History:
5 out of 2,596 
3 out of 243 
Years Active: 2016-2024
Title: The Innovations of Liang-Chuan Wang
Introduction
Liang-Chuan Wang is a prominent inventor based in Philadelphia, PA (US). He has made significant contributions to the field of biomedical research, particularly in the area of cancer treatment and immunotherapy. With a total of 5 patents, his work focuses on enhancing the efficacy of T cell therapies and targeting tumor microenvironments.
Latest Patents
One of his latest patents is titled "Inhibition of diacylglycerol kinase to augment adoptive T cell transfer." This invention provides compositions and methods for inhibiting one or more diacylglycerol kinase (DGK) isoforms in a cell to enhance the cytolytic activity of the cell. In certain embodiments, the cells may be modified to express a chimeric antigen receptor (CAR). The inhibition of DGK in T cells used in adoptive T cell transfer increases the cytolytic activity of the T cells, which may be beneficial in treating various conditions, including cancer, infections, and immune disorders. Another notable patent is "Compositions and methods for targeting stromal cells for the treatment of cancer." This invention focuses on targeting the stromal cell population within a tumor microenvironment. It includes a composition that targets fibroblast activation protein (FAP) and features a chimeric antigen receptor (CAR) comprising an anti-FAP domain, a transmembrane domain, and a CD3zeta signaling domain.
Career Highlights
Liang-Chuan Wang has worked with esteemed institutions such as the University of Pennsylvania and The Wistar Institute of Anatomy & Biology. His research has significantly advanced the understanding of T cell functionality and cancer treatment strategies.
Collaborations
He has collaborated with notable colleagues, including Steven M. Albelda and Carl H. June, who are also recognized for their contributions to cancer research and immunotherapy.
Conclusion
Liang-Chuan Wang's innovative work in the field of immunotherapy and cancer treatment has the potential to transform therapeutic approaches and improve patient outcomes. His patents reflect a commitment to advancing medical science and addressing critical health challenges.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.