Introduction: Liang Cao, based in Bethesda, MD, is a prominent inventor with a remarkable portfolio of 29 patents. His work primarily focuses on cell-based assays and the mechanisms of G-protein-coupled receptors, contributing significantly to advancements in biochemical research and drug discovery.

Latest Patents: Among his latest patents, Cao has developed innovative cell-based assays for G-protein-coupled receptor-mediated activities. These inventions disclose compositions and methods that enable the identification of G-protein-coupled receptors, ligands, and compounds that modulate their activities. His compositions utilize cyclic nucleotide-gated channels and fluorescence dyes to detect changes in intracellular cAMP levels stimulated by receptor activation. Additionally, he has patented cell-based assays using voltage and calcium dyes, employing unique compositions that enhance the sensitivity and accuracy of detecting receptor activities through advanced assays.

Career Highlights: Liang Cao has had an esteemed career, contributing to notable companies such as Human Genome Sciences, Inc. and Atto Bioscience Inc. His expertise in biochemical methodologies and patent generation has positioned him as a key figure in the field.

Collaborations: Throughout his career, Cao has collaborated with distinguished scientists, including Craig A. Rosen and Jing-Shan Hu. These partnerships have furthered the scope of his research and innovations, leading to significant advancements in the understanding of cellular mechanisms.

Conclusion: Liang Cao's extensive work in developing innovative assays and methods for understanding G-protein-coupled receptors showcases his commitment to advancing scientific knowledge. His impactful patents and collaborations exemplify his role as a leading inventor in the biochemical domain, making strides that benefit both research and medicine.

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