Location History:
- Wellesley, MA (US) (2006)
- Berwyn, PA (US) (2008 - 2013)
Company Filing History:
2 out of 1,035 
1 out of 31 Years Active: 2006-2013
Title: Innovations of Inventor Li Yan in Medical Science
Introduction
Li Yan is an accomplished inventor based in Berwyn, PA, USA, holding a total of three patents. His work primarily focuses on advancements in medical science, particularly in treatments related to malignant diseases and tissue remodeling.
Latest Patents
One of Li Yan's notable patents is for "Anti-CD147 antibodies, methods and uses." This invention provides antibodies that are specifically designed to target human CD147, which is associated with malignant diseases, including processes such as the stimulation of matrix metalloproteinases (MMPs) from fibroblast cells induced by tumor cells. These antibodies are crucial in treating various conditions where CD147 plays a pathogenic role, such as diseases affecting the eye, lungs, and cardiovascular system.
Another significant patent is titled, "Non-invasive enzyme screen for tissue remodeling associated conditions." This patent encompasses methods and kits aimed at diagnosing and predicting tissue remodeling-associated conditions through the identification of enzyme complexes in biological samples. Particularly, it addresses the detection of metastatic cancer by identifying high molecular weight enzyme complexes that include MMPs.
Career Highlights
Li Yan has made substantial contributions to the field through his tenure at reputable organizations, including Children's Medical Center Corporation and Centocor Ortho Biotech Inc. His innovative work has paved the way for advancements in the medical community, targeting complex health issues.
Collaborations
Throughout his career, Li Yan has collaborated with esteemed professionals, including Marsha A Moses and Mark Hilary Cunningham. These partnerships have fostered a collaborative environment that nurtures creativity and innovation, significantly impacting their respective fields.
Conclusion
In conclusion, Li Yan's inventions reflect a deep commitment to enhancing medical treatments and diagnostics. His patents, centered on anti-CD147 antibodies and non-invasive diagnostic methods, underscore the importance of innovative solutions in addressing challenging diseases. As he continues to progress in his career, Li Yan's contributions are poised to make lasting impacts on medical science and patient care.