Company Filing History:
26 out of 8,384 
13 out of 2,893 
6 out of 444 
Years Active: 2007-2025
Title: The Innovative Contributions of Li-Huei Tsai
Introduction
Li-Huei Tsai, a prominent inventor based in Cambridge, MA, has made significant contributions to the field of neurodegenerative research and treatment. With an impressive portfolio of 22 patents, her work is primarily focused on innovations that aim to combat diseases such as Alzheimer’s.
Latest Patents
Among her latest patents are cutting-edge inventions that hold promise for improving the treatment of neurodegenerative disorders. One notable patent discusses "Small molecule suppressors of APOE gene expression and cerebral vascular amyloid pathology." This invention provides methods for inhibiting amyloid synthesis in subjects, particularly beneficial for treating diseases linked to amyloid, such as Alzheimer’s disease. The small molecule inhibitors included in this patent are designed to be non-immunosuppressant cyclosporins, alongside their pharmaceutically acceptable salts.
Another significant invention is related to "Compositions of polyhydroxylated benzophenones and methods of treatment of neurodegenerative disorders." This patent focuses on polyhydroxylated benzophenone compounds that are useful in treating various neurodegenerative, neurological, psychiatric, and cognitive diseases, especially those associated with a deficiency in HDAC1 deacetylase activity.
Career Highlights
Li-Huei Tsai has an outstanding career in research and innovation, notably contributing her expertise at esteemed institutions like the Massachusetts Institute of Technology and The General Hospital Corporation. Her commitment to advancing understanding and treatment of neurodegenerative diseases has positioned her as a leading figure in her field.
Collaborations
Throughout her career, Tsai has collaborated with notable professionals, including Stephen J. Haggarty and Edward Holson. These collaborations have fostered advancements in understanding the mechanisms behind neurodegenerative diseases and have catalyzed the development of her groundbreaking patents.
Conclusion
Li-Huei Tsai’s extensive work and innovations are paving the way for future advancements in the treatment of neurodegenerative diseases. With her 22 patents, she continues to contribute to the scientific community’s understanding and treatment of these complex disorders, solidifying her role as a pioneering inventor in the realm of medical research.