This inventor holds 3 USPTO granted patents and 2 published patent applications. Top assignee: Dartmouth College. Active years: 2012-2014.
Company Filing History:
Years Active: 2012-2014
Title: Innovations and Contributions of Inventor Li-Fan Lu
Introduction
Li-Fan Lu is a prominent inventor based in Seattle, WA (US). She has made significant contributions to the field of immunology, particularly in understanding and modulating inflammatory responses. With a total of 3 patents to her name, her work has implications for cancer vaccines and immune response enhancement.
Latest Patents
Li-Fan Lu's latest patents include a method for modulating inflammatory responses. This invention focuses on inhibiting T-cell functional activities by blocking T-cell-mediated mast cell activation. It has been discovered that IL-9 produced by T-cells activates mast cells, which mediate an amplification loop critical for graft tolerance and immune responses to tumors. Additionally, her patent provides a method for enhancing immune responses to vaccines, such as cancer vaccines, and for increasing cell and humoral immunity in a subject. Another notable patent relates to novel regulatory T cell proteins, including one designated PD-L3, which co-stimulates αCD3 proliferation of T cells in vitro. A second protein, identified as T-sTNF, has also been upregulated upon αCD3/αGITR stimulation.
Career Highlights
Li-Fan Lu is affiliated with Dartmouth College, where she continues her research and innovation in immunology. Her work has garnered attention for its potential applications in therapeutic settings, particularly in cancer treatment and vaccine development.
Collaborations
Li-Fan Lu collaborates with esteemed colleagues, including Randolph J Noelle and Sergio Quezada. These partnerships enhance her research capabilities and contribute to the advancement of knowledge in her field.
Conclusion
Li-Fan Lu's innovative work in immunology and her patented methods for modulating immune responses highlight her significant contributions to science. Her research not only advances our understanding of immune mechanisms but also paves the way for new therapeutic strategies.