Inventors with similar research interests:
Location History:
- San Deigo, CA (US) (2017)
- San Diego, CA (US) (2013 - 2023)
Company Filing History:
74 out of 92 
56 out of 59 
1 out of 1 Years Active: 2013-2025
Areas of Expertise:
Title: Innovations and Contributions of Leslie Ann Greene in Biotechnology
Introduction
Leslie Ann Greene, based in San Diego, California, is a prominent inventor celebrated for his significant contributions to biotechnology. With a remarkable portfolio of 74 patents, Greene's innovations aim to advance therapeutic solutions for various diseases, particularly those linked to neuropilin-2 (NRP2) and related biological activities.
Latest Patents
Among Leslie Ann Greene's most recent patents is a groundbreaking invention involving therapeutic compositions that comprise anti-NRP2 antibodies. This invention provides affinity matured and humanized antibodies and antigen-binding fragments that specifically bind to human neuropilin-2 (NRP2) polypeptides. These antibodies play a critical role in modulating binding interactions between NRP2 and its ligands, which subsequently influences NRP2-mediated downstream signaling events. This innovation presents potential therapeutic applications for treating diseases associated with NRP2.
Another noteworthy patent involves compositions and methods comprising histidyl-tRNA synthetase splice variants that exhibit non-canonical biological activities. Greene's research in this area has led to isolated polynucleotides and polypeptides with unique properties, paving the way for new therapeutic methods and compositions.
Career Highlights
Leslie Ann Greene has had an impactful career, working with leading companies in the biotechnology sector. He has notably contributed to Atyr Pharma, Inc. and Pangu Biopharma Limited, where he has been instrumental in driving research and innovation. His focus on diseases related to NRP2 has positioned him as a key figure in advancing therapeutic development in this area.
Collaborations
Throughout his career, Greene has collaborated with esteemed colleagues, including Fei Hong and Jeffry Dean Watkins. These partnerships have allowed for the exchange of ideas and expertise, further enhancing the development of innovative therapies stemming from Greene's research.
Conclusion
Leslie Ann Greene exemplifies the spirit of innovation within the biotechnology field. His extensive patent portfolio reflects his dedication to advancing medical science and offering novel solutions for treating diseases. As he continues to innovate, the contributions of Leslie Ann Greene are likely to have a lasting impact on the field of therapeutic development.
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