The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2023
Filed:
Oct. 02, 2020
Atyr Pharma, Inc., San Diego, CA (US);
Luke Burman, San Diego, CA (US);
Yeeting Chong, San Diego, CA (US);
Leslie Ann Greene, San Diego, CA (US);
David King, Encinitas, CA (US);
Zhiwen Xu, San Diego, CA (US);
Ryan Andrew Adams, San Diego, CA (US);
aTyr Pharma, Inc., San Diego, CA (US);
Abstract
Provided are affinity matured and humanized antibodies and antigen-binding fragments thereof that specifically bind to human neuropilin-2 (NRP2) polypeptides, including those that modulate binding interactions between human NRP2 and at least one NRP2 ligand, and which thereby modulate subsequent NRP2-mediated downstream signaling events, including related therapeutic compositions and methods for modulating NRP2 activity and treating diseases such as NRP2-associated diseases.