Lere Bao

Title: Lere Bao: Innovator in Cancer Diagnostics

Introduction

Lere Bao is a prominent inventor based in Brookline, MA (US), known for his significant contributions to cancer diagnostics. With a total of 10 patents, he has made remarkable strides in understanding and diagnosing various forms of cancer.

Latest Patents

Among his latest patents, Bao has developed methods for the diagnosis and prognosis of cancer. He discovered a protein in humans, referred to as the collagen-like gene (CLG) product, which is expressed in human prostate cancer and breast cancer cell lines but not in normal adult tissues. His research indicates that the level of CLG mRNA expression correlates positively with the metastatic potential of the cancer cell lines tested. Another notable invention is the use of Pin1 as a marker for prostate cancer. This invention provides methods for diagnosing prostate cancer, measuring its aggressiveness, and identifying cases likely to metastasize. The diagnostic and prognostic assays include antibody-based detection of Pin1 and amplification of Pin1 RNA, which can be used alongside other diagnostic methods such as the PSA test and Gleason grading system.

Career Highlights

Lere Bao has worked with notable organizations, including Children's Medical Center Corporation and Pintex Pharmaceuticals, Inc. His work has significantly impacted the field of cancer research and diagnostics, showcasing his dedication to improving patient outcomes.

Collaborations

Throughout his career, Bao has collaborated with esteemed colleagues, including Bruce R. Zetter and Da Gong Wang. These partnerships have further enhanced his research and innovation in cancer diagnostics.

Conclusion

Lere Bao's contributions to cancer diagnostics through his innovative patents and collaborations highlight his role as a leading inventor in the field. His work continues to pave the way for advancements in cancer detection and treatment.