The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 25, 2000
Filed:
Apr. 29, 1998
Applicant:
Inventors:
Bruce R Zetter, W. Newton, MA (US);
Lere Bao, Brookline, MA (US);
Assignee:
Children's Medical Center Corporation, Boston, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; C07K / ;
U.S. Cl.
CPC ...
435-71 ; 5303871 ; 5303879 ; 5303881 ;
Abstract
The present inventors have now discovered that humans have a gene that encodes a novel protein of the thymosin .beta. family. This novel protein, herein referred to as thymosin .beta.15, has the ability to bind and sequester G-actin, like other members of the thymosin .beta. family, but unlike what is known about other members it also directly regulates cell motility in prostatic carcinoma cells. The present invention is direct to an isolated cDNA encoding the human thymosin .beta.15 gene (SEQ ID NO: 1) and have deduced the amino acid sequence (SEQ ID NO: 2).