Company Filing History:

7 out of 410

Promega Corporation

patents

5 out of 69

Ortho Diagnostic Systems Inc.

patents

1 out of 3

Genometrix Genomics Incorporated

patents

Years Active: 1993-2004

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13 patents (USPTO):Sort by Forward Citations

Abstract keywords

1. 6677140 - Nucleic acid amplification with DNA-dependent RNA polymerase activity of RNA replicases (2004-01-13),

2. 6369207 - Nucleic acid amplification with DNA-dependent RNA polymerase activity of RNA replicases (2002-04-09),

3. 6331441 - Multiplexed molecular analysis apparatus and method (2001-12-18),

4. 6090589 - Nucleic acid amplification with DNA-dependent RNA polymerase activity of (2000-07-18),

5. 5783685 - Chemical preparation of high specific activity nucleotide probes (1998-07-21),

6. 5700645 - Methods and kits for separation, concentration and analysis of cells (1997-12-23),

7. 5654149 - Non-radioactive DNA sequencing (1997-08-05),

8. 5587286 - Methods and kits for detection of cells in food materials (1996-12-24),

9. 5538872 - Method of preparing nucleotide probes using a bridging complement (1996-07-23),

10. 5523206 - Non-radioactive DNA sequencing (1996-06-04),

11. 5521298 - High specific activity nucleotide probes having target recognition and (1996-05-28),

12. 5324829 - High specific activity nucleic acid probes having target recognition and (1994-06-28),

13. 5215882 - Method of immobilizing nucleic acid on a solid surface for use in (1993-06-01),

Title: Innovations of Leopoldo G Mendoza

Introduction

Leopoldo G Mendoza is a notable inventor based in Madison, WI (US), recognized for his significant contributions to the field of nucleic acid amplification. With a total of 13 patents to his name, Mendoza has made remarkable advancements that have implications in various scientific and medical applications.

Latest Patents

Mendoza's latest patents focus on the use of DNA-dependent RNA polymerase activity of RNA replicases. His inventions include methods and kits that leverage the discovery that RNA replicases, such as Qβ replicase, exhibit DNA-dependent RNA polymerase (DDRP) activity. This activity allows for the amplification of nucleic acids, including DNA segments and DNA:RNA chimeric segments. The methods developed by Mendoza enable the synthesis of RNA from DNA segments, which can then be autocatalytically replicated. This innovation is particularly useful in detecting nucleic acid analytes through hybridization assays, providing a more efficient means of generating detectable reporter molecules.

Career Highlights

Throughout his career, Mendoza has worked with prominent companies such as Promega Corporation and Ortho Diagnostic Systems Inc. His work has significantly impacted the field of molecular biology and diagnostics, showcasing his expertise and innovative spirit.

Collaborations

Mendoza has collaborated with esteemed colleagues, including Chander Bahl and Edward E Pahuski. These partnerships have further enhanced his research and development efforts, leading to groundbreaking advancements in nucleic acid technologies.

Conclusion

Leopoldo G Mendoza's contributions to the field of nucleic acid amplification through his innovative patents and collaborations highlight his role as a leading inventor. His work continues to influence scientific research and medical diagnostics, paving the way for future advancements.

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