The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 13, 2004
Filed:
Feb. 07, 2002
Randall L. Dimond, Madison, WI (US);
Steven J. Ekenberg, Mt. Horeb, WI (US);
James R. Hartnett, Madison, WI (US);
Geoffrey R. Hudson, Madison, WI (US);
Leopoldo G. Mendoza, Madison, WI (US);
Katharine M. Miller, Verona, WI (US);
John E. Monahan, Walpole, MA (US);
Christopher L. Jones, Madison, WI (US);
Mark A. Maffitt, Madison, WI (US);
Richard A. Martinelli, Brighton, MA (US);
Edward E. Pahuski, Marshall, WI (US);
James W. Schumm, Madison, WI (US);
Promega Corporation, Madison, WI (US);
Abstract
The present invention entails methods and kits for carrying them out based on the discovery that an RNA replicase, such as Q&bgr; replicase, has DNA-dependent RNA polymerase (“DDRP”) activity with nucleic acid segments, including DNA segments and DNA:RNA chimeric segments, which comprise a 2′-deoxyribonucleotide or an analog thereof and which have sequences of RNAs that are autocatalytically replicatable by the replicase.