Moscow, Russia

Leonid E Kholodov


Average Co-Inventor Count = 9.0

ph-index = 1

Forward Citations = 7(Granted Patents)


Company Filing History:


Years Active: 1981

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1 patent (USPTO):Explore Patents

Title: Leonid E Kholodov: Innovator in Chemical Patents

Introduction

Leonid E Kholodov is a notable inventor based in Moscow, Russia. He has contributed to the field of chemistry through his innovative patent related to sydnonimine N-acyl derivatives. His inventive work showcases the intricate method for preparing valuable pharmaceutical compounds, demonstrating his expertise and commitment to research and development.

Latest Patents

Kholodov holds one patent titled "Sydnonimine N-acyl derivatives and method for preparing same." This patent details the structure of N-acyl sydnonimines and outlines a sophisticated method for their synthesis. The formula includes variations where R can be phenyl, beta-phenylethyl, or various forms of alpha-methyl-beta-phenylethyl, with specific configurations for R', X, and R''. The method involves reacting N-nitrosoderivatives of N-substituted nitriles of alpha-amino acids with an acylation agent in a solvent, facilitated by a basic-character catalyst, which ultimately leads to the isolation of the desired product.

Career Highlights

Throughout his career, Kholodov has been associated with esteemed research institutions. He has worked at the All-Union Research Institute of Chemical Pharmaceutical Industry and the Institute of Biophysics. These positions allowed him to collaborate with top professionals in the field and contribute to significant advancements in chemical processes and patents.

Collaborations

During his career, Kholodov has collaborated with notable figures such as Vladimir G Yashunsky and Roald A Altshuler. These collaborations have enriched his work and have been pivotal in pushing the boundaries of research in organic chemistry.

Conclusion

Leonid E Kholodov's contribution to the field of chemistry in Moscow, particularly through his patent on sydnonimine N-acyl derivatives, epitomizes the spirit of innovation and scientific inquiry. His career and collaborations reflect a commitment to advancing knowledge and developing new methodologies that can enhance pharmaceutical chemistry.

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